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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1966634Generated: November 1, 2026

6-(2,2-Difluoro-2-phenylethoxy)-1-hexanamine → {6-[2,2-Difluoro-2-(3-methylphenyl)ethoxy]hexyl}amine

https://huagongshe.com/reaction/1966634

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(2,2-Difluoro-2-phenylethoxy)-1-hexanamineHCID 50993080—
Reactant2-{6-[2,2-Difluoro-2-(3-methylphenyl)ethoxy]hexyl}-1H-isoindole-1,3(2H)-dioneHCID 67246592—
Product{6-[2,2-Difluoro-2-(3-methylphenyl)ethoxy]hexyl}amineHCID 67247388—

Reaction Steps

Obtained from Intermediate 31 (4.0 g, 14.4 mmol) by the procedure described in Intermediate 9. {6-[2,2-Difluoro-2-(3-methylphenyl)ethoxy]hexyl}amine was obtained (1.93 g, 50%) as oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08420669B2
Source datasetuspto-grants-2013_04
ORD IDord-c388be7790604d948ca87547ab8b4f21
Source noteuspto-grants-2013_04