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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1966642Generated: October 30, 2026

2,2-Difluoro-4-phenylbutan-1-ol → 2-(3-Bromophenyl)-2,2-difluoroethanol

https://huagongshe.com/reaction/1966642

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Difluoro-4-phenylbutan-1-olHCID 18425775—
ReactantEthyl 2-(3-bromophenyl)-2,2-difluoroacetateHCID 53419381—
Product2-(3-Bromophenyl)-2,2-difluoroethanolHCID 67246333—

Reaction Steps

Obtained from Intermediate 48 (21.1 g, 75.6 mmol) by the procedure described in Intermediate 2. The title compound was obtained (17.2 g, 96%) as oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08420669B2
Source datasetuspto-grants-2013_04
ORD IDord-0170261bc2c943ba8017375fec126489
Source noteuspto-grants-2013_04