Potassium Cation → 7-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-(1-methylpyrazol-4-yl)furo[3,2-c]pyridin-6-amine

HRID 196669Notes

Reaction equation

HRID 196669 reaction equation
[Br:1][c:2]1[cH:3][o:4][c:5]2[c:6]1[cH:7][n:8][c:9]([NH2:23])[c:10]2[O:11][CH:12]([CH3:13])[c:14]1[c:15]([Cl:22])[c:16]([F:21])[cH:17][cH:18][c:19]1[Cl:20].[C:39](=[O:40])([O-:41])[O-:42].[CH2:45]1[O:46][CH2:47][CH2:48][O:49][CH2:50]1.[CH3:24][n:25]1[n:26][cH:27][c:28]([B:30]2[O:31][C:32]([CH3:33])([CH3:34])[C:35]([CH3:36])([CH3:37])[O:38]2)[cH:29]1.[CH3:52][CH2:53][O:54][C:55]([CH3:56])=[O:57].[K+:43].[K+:44].[OH2:51].[Pd:58]([Cl:59])[Cl:60]>>[c:2]1(-[c:28]2[cH:27][n:26][n:25]([CH3:24])[cH:29]2)[cH:3][o:4][c:5]2[c:6]1[cH:7][n:8][c:9]([NH2:23])[c:10]2[O:11][CH:12]([CH3:13])[c:14]1[c:15]([Cl:22])[c:16]([F:21])[cH:17][cH:18][c:19]1[Cl:20]

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 962WaterHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 24290Palladium ChlorideHCID 312751,4-DioxaneHCID 27739871-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 674022843-Bromo-7-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-6-ylamine

Product 1

HCID 1784672427-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-(1-methylpyrazol-4-yl)furo[3,2-c]pyridin-6-amine

Sources & evidence

ORD record
ord-5021b94e217d4797a8d7b0071d266cc2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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