HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58256459, compound → HCID 44608309, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58256459 | HCID 58256459 | — |
| Reactant | 2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide | HCID 59525619 | — |
| Product | HCID 44608309 | HCID 44608309 | — |
Reaction Steps
5-[2,6-difluoro-4-(1-hydroxy-1-methyl ethyl)phenyl]-2-({4-[(methylsulfonyl)amino]phenyl}amino)thiophene-3-carboxamide was prepared according to the general procedure in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (85 mg, 0.272 mmol) and N-(4-bromophenyl)-N-(methylsulfonyl)methanesulfonamide (89 mg, 0.272 mmol) as the starting materials.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420695B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-49a47bc17a584d9da845ac5436c00fb1 |
| Source note | uspto-grants-2013_04 |