4-(4-Bromo-benzyl)-thiomorpholine 1,1-dioxide → 2-({4-[(1,1-Dioxidothiomorpholin-4-yl)methyl]phenyl}amino)-5-[4-(methyl sulfonyl)phenyl]thiophene-3-carboxamide

Participants

Reaction Steps

2-({4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}amino)-5-[4-(methyl sulfonyl)phenyl]thiophene-3-carboxamide was prepared according to the general procedure in Example 1 using 2-amino-5-[4-(methylsulfonyl)phenyl]thiophene-3-carboxamide (149 mg, 0.503 mmol) and 4-(4-bromobenzyl)thiomorpholine 1,1-dioxide (153 mg, 0.503 mmol) as the starting materials.

Provenance & Evidence