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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1967169Generated: November 1, 2026

HCID 12811505, compound → HCID 44608312, compound

https://huagongshe.com/reaction/1967169

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 12811505HCID 12811505—
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
ProductHCID 44608312HCID 44608312—

Reaction Steps

5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[4-(2H-1,2,3-triazole-2-ylmethyl)phenyl]amino}thiophene-3-carboxamide was prepared according to the general procedure in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (100 mg, 0.320 mmol) and 2-(4-bromobenzyl)-2H-1,2,3-triazole (76 mg, 0.320 mmol) as the starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08420695B2
Source datasetuspto-grants-2013_04
ORD IDord-4df14d8ae1bb42518afa85fda2fcc4c8
Source noteuspto-grants-2013_04