反应详情

This product was prepared from toluene-4-sulfonic acid 2-methyl-5-phenyl-2H-pyrazol-3-yl ester and 3-ethynyl-thiophene following the general procedure for the Sonogashira cross-coupling reaction described above. Chromatography eluent: heptane/EtOAc 95:5; yield (60 mg, 45%); 1H NMR δ (CDCl3): 7.78 (d, J=8.10 Hz, 2H), 7.60 (m, 1H), 7.46-7.29 (m, 4H), 7.22 (m, 1H), 6.77 (s, 1H), 4.05 (s, 3H); LCMS m/z: 264.

1. customfor the Sonogashira cross-coupling reaction
2. customyield (60 mg, 45%)