HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic acid, 3-(chlorosulfonyl)- → 3-{[3-(Ethoxycarbonyl)piperidin-1-yl]sulfonyl}benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic acid, 3-(chlorosulfonyl)- | HCID 77641 | — |
| Reactant | Ethyl nipecotate | HCID 98969 | — |
| Product | 3-{[3-(Ethoxycarbonyl)piperidin-1-yl]sulfonyl}benzoic acid | HCID 3736786 | — |
Reaction Steps
The intended compound (7.12 g, 92%) was produced as a colorless solid according to the method of Reference Example 1 but using 3-(chlorosulfonyl)benzoic acid (5.00 g) and ethyl piperidine-3-carboxylate (7.04 mL) as the starting materials.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420823B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-314e8d541ae049b495de30e4530a0354 |
| Source note | uspto-grants-2013_04 |