4-Isopropylaniline → HCID 728101, compound
Reaction equation
[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[CH:11]([C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[CH:16][CH:15]=1)([CH3:13])[CH3:12]>>[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7]([NH:18][C:17]1[CH:19]=[CH:20][C:14]([CH:11]([CH3:13])[CH3:12])=[CH:15][CH:16]=1)=[O:9]Participants
3
Procedure
The intended compound was produced according to the method of Example 92 but using 5-bromonicotinic acid and 4-isopropylaniline as the starting materials.
Workup
- customThe intended compound was produced
Sources & evidence
- ORD record
- ord-bd9fe05a65144a799cdaba3221d70969
- Source dataset
- uspto-grants-2013_04
- Patent number
- US08420823B2
Reaction notes
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