Ethyl Bromide → HCID 178466080, compound

HRID 1967630Notes

Reaction equation

HRID 1967630 reaction equation
[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:9]1[C:13]([CH3:14])=[C:12]([OH:15])[C:11](=[O:16])[N:10]1[C:17]1[CH:32]=[CH:31][C:20]2[N:21](C(OC(C)(C)C)=O)[CH:22]=[N:23][C:19]=2[CH:18]=1.Br[CH2:34][CH3:35]>>[NH:21]1[C:20]2[CH:31]=[CH:32][C:17]([N:10]3[CH:9]([C:3]4[CH:4]=[CH:5][CH:6]=[C:7]([F:8])[C:2]=4[F:1])[C:13]([CH3:14])=[C:12]([O:15][CH2:34][CH3:35])[C:11]3=[O:16])=[CH:18][C:19]=2[N:23]=[CH:22]1

Participants

3

Reactant 2

HCID 6332Ethyl BromideHCID 58433050HCID 58433050, compound

Product 1

HCID 178466080HCID 178466080, compound

Procedure

The compound was synthesized starting from tert-butyl 5-(2-(2,3-difluorophenyl)-4-hydroxy-3-methyl-5-oxo-2H-pyrrol-1(5H)-yl)-1H-benzo[d]imidazole-1-carboxylate (0.22 g, 0.5 mmol), bromoethane (0.056 ml, 0.75 mmol) and P1-tBu (0.191 ml, 0.75 mmol) according to the method described above.

Workup

  1. customThe compound was synthesized

Sources & evidence

ORD record
ord-cce6be19c517473d8456cf145f5534ac
Source dataset
uspto-grants-2013_04
Patent number
US08420828B2

Reaction notes

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