Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Chloropyrazine-2-carbonitrile | HCID 292465 | — |
| Reactant | HCID 178477366 | HCID 178477366 | — |
| Solvent | Benzene | HCID 241 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 23642189 | HCID 23642189 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Example 1 by using 5-(ethylthio)-1,3,4-thiadiazole-2-thiol (592 mg, 3.33 mmol), NaH (60% dispersion in mineral oil, 146 mg, 3.66 mmol), and 3-chloropyrazine-2-carbonitrile (422 mg, 3.02 mmol) in DMF and benzene (8 ml, 1/1) by stirring at 90° C. under nitrogen atmosphere overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08426358B2 |
|---|
| Source dataset | uspto-grants-2013_04 |
|---|
| ORD ID | ord-fbe4e919e3a5458cb43d6898cbf51c9a |
|---|
| Source note | uspto-grants-2013_04 |
|---|
