HCID 58126947, compound → 1202897-25-3

HRID 1968434Notes

Reaction equation

HRID 1968434 reaction equation
C(OC([C:6]1[N:7]=C[O:9][C:10]=1[CH2:11][C:12]1[CH:17]=[CH:16][C:15]([Cl:18])=[C:14]([F:19])[CH:13]=1)=O)C>Cl>[ClH:18].[NH2:7][CH2:6][C:10](=[O:9])[CH2:11][C:12]1[CH:17]=[CH:16][C:15]([Cl:18])=[C:14]([F:19])[CH:13]=1

Participants

3

Reactant 1

HCID 58126947HCID 58126947, compound

Product 1

HCID 669224141202897-25-3Yield 135.6%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A mixture of the product of example 17 (2.5 g, 10.53 mmol) with hydrochloride acid (6 mol/l, 30 ml) was refluxed for about 3 hours and then cooled to room temperature. The solids were collected by filtration, washed with EA and dried to give the titled product (1.7 g, 81%)

Workup

  1. temperaturewas refluxed for about 3 hours
  2. filtrationThe solids were collected by filtration
  3. washwashed with EA
  4. customdried

Sources & evidence

ORD record
ord-98d170cb48e34a7caa8fa5b311b4af50
Source dataset
uspto-grants-2013_04
Patent number
US08426405B2

Reaction notes

Loading…