Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | 4-Fluoroanthranilic acid | HCID 2724967 | — |
| Product | HCID 178518022 | HCID 178518022 | 78% |
Reaction Steps
2-amino-4-fluorobenzoic acid (1.55 g, 10 mmol) was dissolved into formamide (5 mL) and stirred at 150° C. for 6 h. The mixture was cooled to room temperature with stirring. The precipitate was filtered out and washed with diethyl ether to give 1.3 g of 7-fluoroquinazolin-4-ol (78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08426430B2 |
|---|
| Source dataset | uspto-grants-2013_04 |
|---|
| ORD ID | ord-03bee2ba47bc4732b576827c8608b85d |
|---|
| Source note | uspto-grants-2013_04 |
|---|
