4-Aminopyridinium → HCID 25151979, compound

HRID 1968679Notes

Reaction equation

HRID 1968679 reaction equation
[Cl:1][CH2:2][CH2:3][C:4]([NH:6][C:7]1[CH:12]=[C:11]([S:13](=[O:23])(=[O:22])[N:14]([CH3:21])[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:10]=[CH:9][C:8]=1[NH:24][CH3:25])=[O:5].[NH2:26][C:27]1[CH:32]=[CH:31][NH+:30]=[CH:29][CH:28]=1>CC(C)=O>[Cl-:1].[NH2:26][C:27]1[CH:32]=[CH:31][N+:30]([CH2:2][CH2:3][C:4]([NH:6][C:7]2[CH:12]=[C:11]([S:13](=[O:23])(=[O:22])[N:14]([CH3:21])[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH:10]=[CH:9][C:8]=2[NH:24][CH3:25])=[O:5])=[CH:29][CH:28]=1

Participants

4

Reactant 2

HCID 4442294-AminopyridiniumHCID 58096340HCID 58096340, compound

Product 1

HCID 25151979HCID 25151979, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

3-Chloro-N-(5-(N-methyl-N-phenylsulfamoyl)-2-(methylamino)phenyl)propanamide (1 g, 0.0026 mol) and 4-aminopyridinium (0.73 g, 0.0078 mol) were boiled in anhydrous acetone (50 ml) for 50 h. The residue was filtered and subjected to crystallization from a 10:1 mixture of acetonitrile with ethanol.

Workup

  1. filtrationThe residue was filtered
  2. customsubjected to crystallization from a 10:1 mixture of acetonitrile with ethanol

Sources & evidence

ORD record
ord-db5527cebb60461a88e7fd549604e727
Source dataset
uspto-grants-2013_04
Patent number
US08426433B2

Reaction notes

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