Hydrochloric Acid → HCID 23402142, compound

HRID 1968878Notes

Reaction equation

HRID 1968878 reaction equation
C([O:5][C:6]([CH:8]1[CH2:10][CH:9]1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=1)=[O:7])(C)(C)C.Cl>ClCCl.O1CCOCC1>[N:12]1[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=1[CH:9]1[CH2:10][CH:8]1[C:6]([OH:7])=[O:5]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 67114131HCID 67114131, compound

Product 1

HCID 23402142HCID 23402142, compound

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneSolventHCID 312751,4-DioxaneSolvent

Procedure

To a solution of 2-pyridin-2-yl-cyclopropanecarboxylic acid tert-butyl ester (1.6 g, 7.3 mmol) in dichloromethane (30 mL) was added a solution of anhydrous HCl in dioxane (4.0M, 15 mL). The solution was allowed to stir at ambient temperature overnight then evaporated to yield the product as a yellow oil.

Workup

  1. customthen evaporated

Sources & evidence

ORD record
ord-5015ba9da0a94f50bfa49d41f02ea8ee
Source dataset
uspto-grants-2013_04
Patent number
US08426414B2

Reaction notes

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