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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 196891Generated: October 29, 2026

Bicarbonate Ion → 1-Benzhydryl-3-[1-(3,5-difluorophenyl)-2-fluoro-2-methylpropyl]azetidine

https://huagongshe.com/reaction/196891

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantPyridineHCID 1049—
ReactantDichloromethaneHCID 6344—
ReactantHydrofluoric AcidHCID 14917—
Reactant1-(1-Benzhydrylazetidin-3-yl)-1-(3,5-difluorophenyl)-2-methylpropan-2-olHCID 11475292—
Product1-Benzhydryl-3-[1-(3,5-difluorophenyl)-2-fluoro-2-methylpropyl]azetidineHCID 67065989—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-3086efe571b34c62ad2464ed5ae4281a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)