Bicarbonate Ion → 1-Benzhydryl-3-[1-(3,5-difluorophenyl)-2-fluoro-2-methylpropyl]azetidine
Reaction equation
[Cl:45][CH2:46][Cl:47].[F:1][c:2]1[cH:3][c:4]([CH:9]([C:10]([CH3:11])([OH:12])[CH3:13])[CH:14]2[CH2:15][N:16]([CH:18]([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[CH2:17]2)[cH:5][c:6]([F:8])[cH:7]1.[FH:37].[Na+:39].[Na+:44].[O-:40][C:41]([OH:42])=[O:43].[OH-:38].[n:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1>>[F:1][c:2]1[cH:3][c:4]([CH:9]([C:10]([CH3:11])([CH3:13])[F:37])[CH:14]2[CH2:15][N:16]([CH:18]([c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[CH2:17]2)[cH:5][c:6]([F:8])[cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-3086efe571b34c62ad2464ed5ae4281a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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