HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 4-(Bromomethyl)-3-(trifluoromethyl)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-(Bromomethyl)-3-(trifluoromethyl)benzoic acid | HCID 23145893 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(Bromomethyl)-3-(trifluoromethyl)benzoyl chloride | HCID 25134280 | — |
Reaction Steps
1.00 g of 4-(bromomethyl)-3-(trifluoromethyl)benzoic acid was dissolved in dichloromethane (q.s.), then 2 drops of anhydrous N,N′-dimethylformamide were added. Then 2 ml of oxalyl chloride was added dropwise to the mixture. The reaction mixture was reacted at room temperature for 5 h, and concentrated to provide the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08426446B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-a752c49b7ab5411abf8d79bdfeb05638 |
| Source note | uspto-grants-2013_04 |