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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1969061Generated: November 1, 2026

4-Chlorobenzenesulfonyl chloride → [3-(2-{[(4-Chloro-benzenesulfonyl)-methyl-amino]-methyl}-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid

https://huagongshe.com/reaction/1969061

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorobenzenesulfonyl chlorideHCID 7398—
Reactant[3-(2-Methylaminomethyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acidHCID 58288535—
Product[3-(2-{[(4-Chloro-benzenesulfonyl)-methyl-amino]-methyl}-4-trifluoromethyl-phenoxy)-phenyl]-acetic acidHCID 44539244—

Reaction Steps

Prepared according to the procedure described in Example 22, Step 1, using the following starting materials: [3-(2-methylaminomethyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid and 4-chlorobenzenesulfonyl chloride. M+H=514.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08426449B2
Source datasetuspto-grants-2013_04
ORD IDord-3e79c330782c4ceda368105d2903b58c
Source noteuspto-grants-2013_04