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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1969087Generated: November 1, 2026

Ethylamine → HCID 58288476, compound

https://huagongshe.com/reaction/1969087

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
ReactantSodium cyanoborohydrideHCID 5003444—
ReactantHCID 58288506HCID 58288506—
SolventDichloromethaneHCID 6344—
ProductHCID 58288476HCID 58288476—

Reaction Steps

[3-(2-Formyl-4-nitro-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester (1.0 g, 2.79 mmol), ethylamine (2M in THF; 2.8 mL, 5.6 mmol), and sodium cyanoborohydride (0.26 g, 4.2 mmol) were combined in CH2Cl2 (30 mL), and the reaction was stirred at room temperature for 3 hours. After work-up, the mixture was concentrated to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08426449B2
Source datasetuspto-grants-2013_04
ORD IDord-5fb5000e6b17484f876be21bd036822f
Source noteuspto-grants-2013_04