Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methane | HCID 297 | — |
| Reactant | 1,1-Dimethylhydrazine | HCID 5976 | — |
| Reactant | HCID 58288466 | HCID 58288466 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 58288533 | HCID 58288533 | — |
Reaction Steps
(3-{2-[(Benzyloxycarbonyl-ethyl-amino)-methyl]-4-nitro-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester (0.1 g, 0.19 mmol), 1,1-dimethylhydrazine (0.1 g, 1.3 mmol), ferric chloride (0.01 g), and DARCO (0.05 g) were combined in EtOH (5 mL), and the reaction was stirred at 65° C. until complete. The mixture was worked up to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08426449B2 |
|---|
| Source dataset | uspto-grants-2013_04 |
|---|
| ORD ID | ord-4796098ef68b43a4926e0d825d6d11a2 |
|---|
| Source note | uspto-grants-2013_04 |
|---|
