反应详情

温度

65 °C

(3-{2-[(Benzyloxycarbonyl-ethyl-amino)-methyl]-4-nitro-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester (0.1 g, 0.19 mmol), 1,1-dimethylhydrazine (0.1 g, 1.3 mmol), ferric chloride (0.01 g), and DARCO (0.05 g) were combined in EtOH (5 mL), and the reaction was stirred at 65° C. until complete. The mixture was worked up to give the title compound.