Diethyl Ether → Ethyl 6-hydroxy-6-(5-isopropoxy-3-pyridinyl)-3-azabicyclo[3.2.1]octane-3-carboxylate
Reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][c:6]([O:8][CH:9]([CH3:10])[CH3:11])[cH:7]1.[CH2:12]([Li:13])[CH2:14][CH2:15][CH3:16].[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[O:17]=[C:18]1[CH:19]2[CH2:20][N:21]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[CH2:22][CH:23]([CH2:24]1)[CH2:25]2>>[c:2]1([C:18]2([OH:17])[CH:19]3[CH2:20][N:21]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[CH2:22][CH:23]([CH2:24]2)[CH2:25]3)[cH:3][n:4][cH:5][c:6]([O:8][CH:9]([CH3:10])[CH3:11])[cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-70e1e2afe8984f33b7170a5d81bef6d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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