2-Amino-4-methylphenol → HCID 68742270, compound

HRID 1969294Notes

Reaction equation

HRID 1969294 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[OH:9].[F:10][C:11]([F:26])([F:25])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[C:18]1[O:22][C:21]([CH:23]=O)=[CH:20][CH:19]=1>>[CH3:8][C:6]1[CH:5]=[CH:4][C:3]([OH:9])=[C:2]([N:1]=[CH:23][C:21]2[O:22][C:18]([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[C:11]([F:25])([F:10])[F:26])=[CH:19][CH:20]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 72642-Amino-4-methylphenolHCID 6882805-[2-(trifluoromethyl)phenyl]furan-2-carbaldehyde

Product 1

HCID 68742270HCID 68742270, compound

Procedure

Using 2-amino-4-methylphenol and 5-(2-(trifluoromethyl)phenyl)furan-2-carbaldehyde, 3.82 g of 4-methyl-2-{[5-(2-(trifluoromethyl)phenyl)furan-2-yl]methyleneamino}phenol were obtained as a yellow powder (yield 92%).

Sources & evidence

ORD record
ord-5f4a0b89b235488f89a7006c71cf8cbc
Source dataset
uspto-grants-2013_04
Patent number
US08426540B2

Reaction notes

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