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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1969963Generated: October 30, 2026

Benzyl Bromide → HCID 21139221, compound

https://huagongshe.com/reaction/1969963

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
Reactant2-oxo-2,3-dihydro-1H-indole-5-sulfonyl chlorideHCID 4962506—
ProductHCID 21139221HCID 2113922187%

Reaction Steps

5-Phenylmethanesulfonyl-1,3-dihydro-indol-2-one was prepared according to the method described by Jiong Jack Chen et al. (Organic Process Research and Development, 2003, 7, 313-317) from 1 g (4.32 mmol) of 2-oxo-2,3-dihydro-1H-indole-5-sulfonyl chloride and 0.51 mL (4.32 mmol) of bromomethyl-benzene. After filtration and washing with acetone, 1.08 g (87%) of 5-phenylmethanesulfonyl-1,3-dihydro-indol-2-one is obtained in the form of a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08426437B2
Source datasetuspto-grants-2013_04
ORD IDord-09150f3ce2b944879c4ca4c0b7a8995a
Source noteuspto-grants-2013_04