HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → HCID 86627524, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Oxindole | HCID 321710 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | 5-Benzoyl-1,3-dihydro-2H-indol-2-one | HCID 13408164 | — |
| Product | HCID 86627524 | HCID 86627524 | — |
Reaction Steps
Synthesis of 5-benzoyl-1,3-dihydro-indol-2-one is described by McNutt (WO99/10325). This compound was prepared according to this procedure from 665 g (5 mmol) of 1,3-dihydro-indol-2-one, aluminium trichloride (15 mmol) and benzoyl chloride (10 mmol) to give, after trituration in water and drying, 880 mg (74%) of 5-benzoyl-1,3-dihydro-indol-2-one in the form of a beige solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08426437B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-b4a47cf161944e5da39d7a75c6b7b09f |
| Source note | uspto-grants-2013_04 |