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HRID1970012

反应详情

EQUATION

反应方程式

HRID 1970012 的结构方程式

REACTANTS

反应物

2
结构：CNC.Cl
HCID10473

N-Methylmethanamine hydrochloride

C2H8ClN

结构：O=C(O)c1c[nH]c2c(=O)[nH]c3ccc(S(=O)(=O)Cl)cc3c12
HCID45121068

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)S(=O)(=O)c1ccc2[nH]c(=O)c3[nH]cc(C(=O)O)c3c2c1
HCID68565688

未命名化合物

PROCEDURE

实验过程

8-Dimethylsulfamoyl-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid is prepared according to synthesis 178, from 326 mg (1 mmol) of 8-chlorosulfonyl-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid and 85 mg (1.05 mmol) of dimethylamine hydrochloride to give, after purification by precipitation and trituration in water, 210 mg (62%) of 8-dimethylsulfamoyl-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid in the form of a gray solid.

WORKUP

后处理

  1. customto give
  2. customafter purification
  3. customby precipitation and trituration in water