HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[1-(2-Methoxyethyl)pyrrolidin-3-YL]-N-methylmethanamine → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-{[1-(2-methoxy-ethyl)-pyrrolidin-3-ylmethyl]-methyl-amino}-thiazol-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[1-(2-Methoxyethyl)pyrrolidin-3-YL]-N-methylmethanamine | HCID 17998751 | — |
| Reactant | 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-propylsulfanyl-thiazolidin-4-one | HCID 86656530 | — |
| Product | 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-{[1-(2-methoxy-ethyl)-pyrrolidin-3-ylmethyl]-methyl-amino}-thiazol-4-one | HCID 67348856 | — |
Reaction Steps
5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-{[1-(2-methoxy-ethyl)-pyrrolidin-3-ylmethyl]-methyl-amino}-thiazol-4-one was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-propylsulfanyl-thiazolidin-4-one and [1-(2-Methoxy-ethyl)-pyrrolidin-3-ylmethyl]-methyl-amine following General Procedure B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08426604B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-af1b6f7244a94efab5974d90dcbd0c34 |
| Source note | uspto-grants-2013_04 |