反应详情

To a solution of 4-[Methyl-(2,2,2-trifluoro-acetyl)-amino]-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester (0.26 g, 0.73 mmol) in methanol (3 mL) was added an aqueous 1.0M solution of potassium carbonate. The reaction mixture was stirred at room temperature for 5 hours and the solvent evaporated in vacuo to yield the title compound which was used directly without further purification.

1. customthe solvent evaporated in vacuo