Acetonitrile → 6-Bromo-N2-(1-(5,7-difluoroquinolin-6-yl)ethyl)pyrazine-2,3-diamine
Reaction equation
[Br:16][c:17]1[c:18]([NH2:24])[n:19][cH:20][c:21]([Br:23])[n:22]1.[CH3:34][C:35]#[N:36].[CH:25]([N:26]([CH2:27][CH3:28])[CH:29]([CH3:30])[CH3:31])([CH3:32])[CH3:33].[F:1][c:2]1[c:3]2[cH:4][cH:5][cH:6][n:7][c:8]2[cH:9][c:10]([F:15])[c:11]1[CH:12]([CH3:13])[NH2:14]>>[F:1][c:2]1[c:3]2[cH:4][cH:5][cH:6][n:7][c:8]2[cH:9][c:10]([F:15])[c:11]1[CH:12]([CH3:13])[NH:14][c:17]1[c:18]([NH2:24])[n:19][cH:20][c:21]([Br:23])[n:22]1Participants
5
Sources & evidence
- ORD record
- ord-f51f7b5d210c4f71b16bca8489693184
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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