反应详情

To a solution of 15.5 g 5-benzyloxycarbonylmethoxy-1-phenyl-1H-pyrazole-3-carboxylic acid ethyl ester in 100 ml ethyl acetate was added 1 g Pd/C (10%) and the resulting suspension stirred under an atmosphere of hydrogen (1 bar) for 24 h. The reaction mixture was filtered over a plug of Celite, washed with ethyl acetate and methanol giving the crude product after evaporation of the solvents. Yield: 9.5 g colorless platelets.

1. filtrationThe reaction mixture was filtered over a plug of Celite
2. washwashed with ethyl acetate and methanol giving the crude product
3. customafter evaporation of the solvents