反应详情

To a stirred solution of cyclopropane carboxaldehyde (57.8 g, 825 mmol) in DCM (825 mL) were added 2-methyl-2-propanesulfinamide (50 g, 413 mmol), magnesium sulfate (248 g, 2.06 mol), and PPTS (5.18 g, 20.6 mmol). The reaction mixture was left to stir for 1 day, filtered through a fritted glass, concentrated, and purified by filtration through SiO2 using 40% EtOAc in Hex as an eluent.

1. waitThe reaction mixture was left
2. filtrationfiltered through a fritted glass
3. concentrationconcentrated
4. filtrationpurified by filtration through SiO2 using 40% EtOAc in Hex as an eluent