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HRID1971125

反应详情

EQUATION

反应方程式

HRID 1971125 的结构方程式

REACTANTS

反应物

3
结构：CNC
HCID674

Dimethylamine

C2H7N

结构：CC(C)(C)[C@H](N)C(=O)O
HCID164608

3-Methyl-L-valine

C6H13NO2

结构：CNC(=O)[C@H](CC(C)C)NC(=O)c1nc(Br)n2c1CN(C)CCC2
HCID57635259

未命名化合物

2 次

PRODUCTS

生成物

1
结构：CN1CCCn2c(Br)nc(C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C)c2C1
HCID57635558

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

This intermediate was prepared following the synthesis of ((S)—N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-3-bromo-8-methyl-6,7,8,9-tetrahydro-5H-imidazo[1,5-a][1,4]diazepine-1-carboxamide (Intermediate 55B) by replacing Z-Leu-OH with tert-Leu-OH, and replacing methylamine hydrochloride with dimethylamine solution in THF. LCMS (+ESI) m/z 417.1 [M+H]+.

WORKUP

后处理

  1. customThis intermediate was prepared