Pyrazole → HCID 60926125, compound

HRID 1971241Notes

Reaction equation

HRID 1971241 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-])=O)=[CH:4][C:3]=1[C:11]([F:14])([F:13])[F:12].[NH:15]1[CH:19]=[CH:18][CH:17]=[N:16]1>>[N:15]1([C:2]2[CH:7]=[CH:6][C:5]([NH2:8])=[CH:4][C:3]=2[C:11]([F:14])([F:13])[F:12])[CH:19]=[CH:18][CH:17]=[N:16]1

Participants

3

Reactant 2

HCID 1048PyrazoleHCID 949542-Fluoro-5-nitrobenzotrifluoride

Product 1

HCID 60926125HCID 60926125, compound

Procedure

The title compound is obtained in a similar manner as Example 71a using 1-fluoro-4-nitro-2-trifluoromethyl-benzene (Aldrich, Buchs, Switzerland) and pyrazole (Fluka, Buchs, Switzerland). Title compound: ES-MS: 228 (M+H)+; analytical HPLC: tret=4.58 minutes (Grad 2).

Sources & evidence

ORD record
ord-009880c1ab6d4d649fa9a6156dfbc35e
Source dataset
uspto-grants-2013_04
Patent number
US08431592B2

Reaction notes

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