反应详情

1.0 g (4.56 mmol) N-[4-(4-fluorphenyl)-1H-imidazole-2-yl]acetamide were suspended in 30 ml 2 N HCl and 30 ml ethanol and were stirred at 80° C. for 2 hours. After removal of the solvent under vacuum, 0.97 g 4-(4-fluorphenyl)-1H-imidazole-2-aminium chloride were obtained, which was used in the following reaction without further purification.

1. customAfter removal of the solvent under vacuum