Chlorobenzene → 4'-[(4-{trans-4-[3-Fluoro-2-(fluoromethyl)-2-hydroxypropoxy]cyclohexyl}-5-oxo-7-propyl-4,5-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)methyl]biphenyl-2-carbonitrile
Reaction equation
[Cl:44][c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1.[F:1][CH2:2][C:3]1([CH2:6][O:7][CH:8]2[CH2:9][CH2:10][CH:11]([n:14]3[c:15]4[n:16]([c:17]([CH2:36][CH2:37][CH3:38])[c:18]([CH2:21][c:22]5[cH:23][cH:24][c:25](-[c:28]6[c:29]([C:34]#[N:35])[cH:30][cH:31][cH:32][cH:33]6)[cH:26][cH:27]5)[c:19]3=[O:20])[n:39][cH:40][n:41]4)[CH2:12][CH2:13]2)[O:4][CH2:5]1.[FH:42].[K:43]>>[F:1][CH2:2][C:3]([OH:4])([CH2:5][F:42])[CH2:6][O:7][CH:8]1[CH2:9][CH2:10][CH:11]([n:14]2[c:15]3[n:16]([c:17]([CH2:36][CH2:37][CH3:38])[c:18]([CH2:21][c:22]4[cH:23][cH:24][c:25](-[c:28]5[c:29]([C:34]#[N:35])[cH:30][cH:31][cH:32][cH:33]5)[cH:26][cH:27]4)[c:19]2=[O:20])[n:39][cH:40][n:41]3)[CH2:12][CH2:13]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-2a6a92813604435bbf45522a6170d2f0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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