反应详情

A solution of 900 mg of 10e in 15 ml of isopropyl amine was stirred for 3 days at RT. The reaction mixture was concentrated. The residue was treated with 10 ml of sat. NaHCO3 and extracted with ethyl acetate. After drying and concentration of the organic material 750 mg of essentially pure 10f was obtained as an oil.

1. concentrationThe reaction mixture was concentrated
2. additionThe residue was treated with 10 ml of sat. NaHCO3
3. extractionextracted with ethyl acetate
4. customAfter drying