HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → Tert-butyl 2-(isopropylamino)ethyl(prop-2-ynyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 2-(Tert-butoxycarbonyl(prop-2-ynyl)amino)ethyl methanesulfonate | HCID 58124892 | — |
| Product | Tert-butyl 2-(isopropylamino)ethyl(prop-2-ynyl)carbamate | HCID 58124856 | — |
Reaction Steps
A solution of 900 mg of 10e in 15 ml of isopropyl amine was stirred for 3 days at RT. The reaction mixture was concentrated. The residue was treated with 10 ml of sat. NaHCO3 and extracted with ethyl acetate. After drying and concentration of the organic material 750 mg of essentially pure 10f was obtained as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431564B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-d5805bf584344fd1ab24103e16635913 |
| Source note | uspto-grants-2013_04 |