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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1971805Generated: November 2, 2026

Hydrochloric Acid → HCID 68983762, compound

https://huagongshe.com/reaction/1971805

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthyl AcetateHCID 8857—
ReactantHCID 57912458HCID 57912458—
SolventDiethyl EtherHCID 3283—
ProductHCID 68983762HCID 68983762—

Reaction Steps

To a mixture of N-(cyclopropylmethyl)-3-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-6-methoxy-N-(tetrahydro-2H-pyran-4-yl)pyrazolo[5,1-b][1,3]thiazole-7-amine (8.38 mg) and ethyl acetate (0.5 mL) was added hydrochloric acid in diethyl ether (1M, 17.2 μL). The mixture was stirred at room temperature for 1.5 hours and the solvent was removed by blowing nitrogen stream and dried to obtain the title compound (9.22 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08431603B2
Source datasetuspto-grants-2013_04
ORD IDord-c1fc64b157814c95817a18919fa4d273
Source noteuspto-grants-2013_04