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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1971811Generated: November 3, 2026

Hydrochloric Acid → HCID 68516475, compound

https://huagongshe.com/reaction/1971811

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthyl AcetateHCID 8857—
ReactantHCID 44478736HCID 44478736—
SolventDiethyl EtherHCID 3283—
ProductHCID 68516475HCID 68516475—

Reaction Steps

To a mixture of 4-{7-[(cyclopropylmethyl)(tetrahydro-2H-pyran-4-ylmethyl)amino]-6-methoxypyrazolo[5,1-b][1,3]thiazol-3-yl}-3,5-dimethoxybenzonitrile (26.4 mg) and ethyl acetate (0.5 mL) was added hydrochloric acid in diethyl ether (1M, 54.7 μL). The mixture was stirred at room temperature for 1 hour and the solvent was removed by blowing nitrogen stream and dried to obtain the title compound (28.4 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08431603B2
Source datasetuspto-grants-2013_04
ORD IDord-6ef5aef3fe6f43a6aac72fd10ab426e6
Source noteuspto-grants-2013_04