HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68516475, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | HCID 44478736 | HCID 44478736 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 68516475 | HCID 68516475 | — |
Reaction Steps
To a mixture of 4-{7-[(cyclopropylmethyl)(tetrahydro-2H-pyran-4-ylmethyl)amino]-6-methoxypyrazolo[5,1-b][1,3]thiazol-3-yl}-3,5-dimethoxybenzonitrile (26.4 mg) and ethyl acetate (0.5 mL) was added hydrochloric acid in diethyl ether (1M, 54.7 μL). The mixture was stirred at room temperature for 1 hour and the solvent was removed by blowing nitrogen stream and dried to obtain the title compound (28.4 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431603B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-6ef5aef3fe6f43a6aac72fd10ab426e6 |
| Source note | uspto-grants-2013_04 |