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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1971812Generated: November 3, 2026

Hydrochloric Acid → HCID 68517551, compound

https://huagongshe.com/reaction/1971812

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthyl AcetateHCID 8857—
ReactantHCID 44478737HCID 44478737—
SolventDiethyl EtherHCID 3283—
ProductHCID 68517551HCID 68517551—

Reaction Steps

To a mixture of N-(Cyclopropylmethyl)-6-methoxy-N-(tetrahydro-2H-pyran-4-ylmethyl)-3-(2,4,6-trimethoxyphenyl)-pyrazolo[5,1-b][1,3]thiazole-7-amine (6.51 mg) and ethyl acetate (0.5 mL) was added hydrochloric acid in diethyl ether (1M, 13.4 μL). The mixture was stirred at room temperature for 1.5 hours and the solvent was removed by blowing nitrogen stream and dried to obtain the title compound (7.41 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08431603B2
Source datasetuspto-grants-2013_04
ORD IDord-2f31f1b405004b3b90e915b6de3fe4c0
Source noteuspto-grants-2013_04