HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphoric Acid → HCID 68515563, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphoric Acid | HCID 1004 | — |
| Reactant | HCID 57912431 | HCID 57912431 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 68515563 | HCID 68515563 | — |
Reaction Steps
To a mixture of 3-{4-[(cyclobutyloxy)methyl]-2,6-dimethoxyphenyl}-6-methoxy-N-propyl-N-(tetrahydro-2H-pyran-4-yl)pyrazolo[5,1-b][1,3]thiazole-7-amine (30.0 mg) and ethyl acetate (0.6 mL) was added phosphoric acid (14.6M, 4.00 μL). The mixture was stirred at room temperature for 5 minutes and the solvent was removed by blowing nitrogen stream and dried to obtain the title compound (36.1 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431603B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-6576f56cdb7f4b6bb73b452360fc27c3 |
| Source note | uspto-grants-2013_04 |