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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1971841Generated: October 26, 2026

4-Fluoro-2-(morpholine-4-sulfonyl)-phenol → tert-Butyl-4-(2-(6-(benzyloxy)-7-((1-(4-fluorophenyl)-3-oxopropan-2-ylthio)carbonyl)-5-oxoimidazo[1,2-a]pyrimidin-1(5H)-yl)acetyl)piperazine-1-carboxylate

https://huagongshe.com/reaction/1971841

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-(morpholine-4-sulfonyl)-phenolHCID 58126990—
Reactant6-(Benzyloxy)-1-(2-(4-(tert-butoxycarbonyl)piperazin-1-yl)-2-oxoethyl)-5-oxo-1,5-dihydroimidazo[1,2-a]pyrimidine-7-carbothioic S-acidHCID 123337387—
Producttert-Butyl-4-(2-(6-(benzyloxy)-7-((1-(4-fluorophenyl)-3-oxopropan-2-ylthio)carbonyl)-5-oxoimidazo[1,2-a]pyrimidin-1(5H)-yl)acetyl)piperazine-1-carboxylateHCID 87206166—

Reaction Steps

Adapted from the procedure of example 39 using the product of example 109 and the product of example 84

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08431581B2
Source datasetuspto-grants-2013_04
ORD IDord-5be1c17d35054ea7b57df5cce9ea9cf5
Source noteuspto-grants-2013_04