反应详情

{2-[5-(4-Benzyloxy-phenyl)-6-butyl-pyridazin-3-yloxy]-ethyl}-diethyl-amine was dissolved in 4.0 M HCl in dioxane and the solvent was evaporated. The resultant salt was washed with ether and dried to provide the title compound (19 mg). LCMS: m/z 435 [M+1]. 1H NMR (400 MHz, CD3OD) δ 7.89 (1H, s), 7.50-7.53 (2H, m), 7.45-7.47 (2H, m), 7.36-7.40 (2H, m), 7.30-7.34 (1H, m), 7.20-7.24 (2H, m), 5.20 (2H, S), 3.74 (2H, t), 3.35-3.42 (4H, m), 3.15 (2H, t), 1.48-1.53 (2H, m), 1.4 (6H, t), 1.21-1.32 (4H, m), 0.81 (3H, t).

1. customthe solvent was evaporated
2. washThe resultant salt was washed with ether
3. customdried