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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1972176Generated: October 30, 2026

Hydrochloric Acid → HCID 86640991, compound

https://huagongshe.com/reaction/1972176

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 86640990HCID 86640990—
SolventDichloromethaneHCID 6344—
ProductHCID 86640991HCID 8664099175%

Reaction Steps

tert-Butyl 4-(2-(4-(2-methylpyridin-3-yloxy)-5-(thieno[3,2-b]pyridin-7-ylthio)pyridin-2-ylamino)thiazol-4-yl)piperidine-1-carboxylate (0.14 g, 0.22 mmol was dissolved in dichloromethane (2 mL) and charged with HCl (2N in diethyl ether, 3 mL). After stirring at ambient temperature for 2 hours, the solution was concentrated and dried under high vacuum to give the title compound (0.10 g, 75% yield) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08431713B2
Source datasetuspto-grants-2013_04
ORD IDord-7d20fe29f395492996611b5d73ad6ae8
Source noteuspto-grants-2013_04