Sodium Hydroxide → HCID 86653824, compound

Participants

Reaction Conditions

Reaction Steps

To 2-(N-acetylamino)-5-bromooctanoic acid (3.0 g), 20 ml of water was added and 1N NaOH was added to adjust the pH to 8. After warming to 37° C., 400 mg of Aspergillus genus aminoacylaze was added, followed by stirring for 24 hours. After cooling in an ice bath, the obtained precipitate was collected by filtration. The product obtained by filtration was washed with water and ethanol until color disappeared. After drying, 658 mg (52%) of (S)-2-amino-5-bromooctanoic acid was obtained as a white crystal.

Provenance & Evidence