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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1972219Generated: November 1, 2026

HCID 86645369, compound → HCID 68701248, compound

https://huagongshe.com/reaction/1972219

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86645369HCID 86645369—
SolventDichloromethaneHCID 6344—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 68701248HCID 68701248—

Reaction Steps

tert-Butyl 2-(2-(3-(4-(4-chlorophenoxy)phenyl)-2-oxo-4-(3-(trifluoromethyl)phenyl)-imidazolidin-1-yl)acetamido)acetate (20.0 mg, 0.0332 mmol) is dissolved in a mixture solvent of DCM (0.4 mL) and TFA (0.4 mL). The reaction mixture is stirred at room temperature for 3 h before removal of the solvent. The residue is purified by reparative LC/MS to provide the title compound; HPLC-MS calculated for C26H21ClF3N3O5 (M+H+) 548.1, found 548.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08431607B2
Source datasetuspto-grants-2013_04
ORD IDord-6b5084f44b084365aae099a9aa4adb03
Source noteuspto-grants-2013_04