Dichloromethane → 4-(4-(Trifluoromethyl)phenoxy)piperidine
Reaction equation
[CH2:32]([Cl:33])[Cl:34].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([O:7][CH:8]2[CH2:9][CH2:10][N:11]([C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH2:12][CH2:13]2)[cH:21][cH:22]1)([F:23])[F:24].[OH:25][C:26]([C:27]([F:28])([F:29])[F:30])=[O:31]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([O:7][CH:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:21][cH:22]1)([F:23])[F:24]Participants
4
Sources & evidence
- ORD record
- ord-ae8ea8148e584a9facbd4ce11f75e626
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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