HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → 3-Cyclopropylthiomorpholine 1,1-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 3-Cyclopropylthiomorpholine 1,1-dioxide hydrochloride | HCID 66582649 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-Cyclopropylthiomorpholine 1,1-dioxide | HCID 64437345 | 96.7% |
Reaction Steps
A 100 mL round-bottomed flask was charged with 3-cyclopropylthiomorpholine 1,1-dioxide hydrochloride (1.00 g, 4.72 mmol) and 10 mL of EtOAc. To this was added 15 mL of saturated aqueous NaHCO3. After stirring at room temperature for 15 min, the layers were separated. The organics were dried (MgSO4), filtered, and concentrated to give 3-cyclopropylthiomorpholine 1,1-dioxide (0.800 g) as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431563B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-7149c6430c64448da0520be0a75968d2 |
| Source note | uspto-grants-2013_04 |