Ammonium Hydroxide → HCID 66582681, compound

Participants

Reaction Conditions

Reaction Steps

5-((4-Bromophenyl)sulfonyl)-2-chloropyridine (98 mg, 0.29 mmol), concentrated NH4OH (3 mL), and EtOH (3 mL) were added to a high-pressure reaction vessel. The vessel was sealed and heated at 120° C. for 18 h. After cooling to room temperature, the solvent was partially removed under vacuum. The white precipitate obtained was filtered, washed with ether, and dried under vacuum to provide 5-((4-bromophenyl)sulfonyl)-2-pyridinamine (75 mg) as a white solid.

Provenance & Evidence